摘要
随着肥胖发生率的日益增高,其危害性在全球已受到广泛关注。多项研究证实,肥胖及其并发症可使心脑血管疾患的发病年龄提前、药物及有创治疗阻力增大、死亡率明显升高,还可能导致心脏的结构、电生理及心肌功能损伤,尤其对于女性患者更具有显著意义。反之,心脏损伤亦可影响减肥方式的选择及综合预后。本文总结了肥胖及其并发症与心血管疾病的关系,并对心血管疾病的预防提出新思考。
Obesity is becoming increasingly prevalent and thus has been a global public concern. Studies have demonstrated that obesity and its complications can cause an early onset of cardiovascular diseases ( CVD), reduce the therapeutic effecacy of medical and invasive treatment, and thus increase the mortality. Meanwhile, it can also cause damage to the structure, electrophysiology, and myocardial function of heart. It can be a particularly important issue for women. On the other hand, heart injury can also affect the weight loss options and their outcomes. This article elucidates the relationship between obesity and its complications and CVD, and meanwhile proposes some new perspectives about the prevention of CVI).
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2012年第4期431-436,共6页
Acta Academiae Medicinae Sinicae
关键词
肥胖
胰岛素抵抗
心血管疾病
obesity
insulin resistance
cardiovascular disease