摘要
[目的]观察比较不同比重布比卡因腰-硬联合麻醉临床应用于剖宫产术的效果、并发症和安全性。[方法]选择ASAⅠ～Ⅱ级择期选取腰麻-硬膜外联合阻滞麻醉(CSEA)的产妇150例,随机分为3组。L组50例产妇为轻比重组,腰麻药为0.75%布比卡因2 mL+无菌注射用水1 mL;I组50例产妇为等比重组,腰麻药为0.75%布比卡因2mL+生理盐水1 mL;H组50例产妇为重比重组,腰麻药为0.75%布比卡因2 mL+10%葡萄糖1 mL。硬膜外导管向头侧置管3～4 cm,阻滞不完全者由硬膜外导管注入2%利多卡因联合麻醉。比较分析3组患者麻醉效果,术中不良反应及神经系统并发症的差异。[结果]3组患者麻醉从麻醉效果来看,起效时间及达到最高阻滞平面的时间,H组均小于其他两组,差异有显著性意义(P<0.05),L组起效时间最长,出现阻滞不完全,需追加2%利多卡因的例数较多,差异有显著性意义(P<0.05)。H组最高平面维持时间大于其他两组,差异有显著性意义(P<0.05),但术中仰卧位综合征及术后神经系统并发症的发生均高于其他两组,差异有显著性意义(P<0.05)。[结论]3种不同比重腰麻液中,0.5%等比重布比卡因用于CSEA剖宫产术效果确切,神经系统并发症少,安全可靠。
[Objective] Evaluating the effectiveness and complications by using bupivicaine at different specific gravity on CSEA for caesarean section.[Methods] 150 parturient（ASAⅠ～Ⅱ） were randomly divided into three groups： L group with 0.75% bupivicaine 2 mL and water for injection 1 mL as spinal fluid;I group with 0.75% bupivicaine 2 mL and normal saline 1 mL;H group with 0.75% bupivicaine 2 mL and 10% glucose 1 mL.2% lidocaine was supplemented via epidural catheter if necessary.[Results] The onset time and the duration of reaching the height level of group H is shorter than the other.（P〈0.05）.There was more incomplete block in group L（P〈0.05）.The highest level maintenance time of group H was longer than the other（P〈0.05）,supine syndrome and negative effect on nervous function were more than the other groups too（P〈0.05）.[Conclusions] 0.5% isotonic specific gravity bupivicaine for CSEA is effective and safe for caesarean section.
出处
《大连医科大学学报》
CAS
2012年第4期390-392,共3页
Journal of Dalian Medical University
关键词
比重
布比卡因
CSEA剖宫产术
阻滞平面
神经功能
specific gravity
bupivicaine
combined spinal and epidural anesthesia（CSEA）
caesarean section
nervous function
