摘要
报告1例阴茎恶性黑素瘤。患者男,71岁。阴茎龟头黑褐色丘疹、水疱3个月,糜烂溃疡1个月。皮肤科检查:阴茎龟头、冠状沟散在多颗粟粒状、绿豆样黑褐色丘疹,颜色较深,周围见浅褐色斑疹、斑丘疹,龟头左上方近冠状沟处有-0.6 cm×0.6 cm溃疡,表面污秽、结痂,有少许浆液性分泌物。皮损组织病理检查:表皮部分缺损,棘层增生,基底层及真皮内见成巢分布的黑素细胞,胞质丰富,嗜酸性,胞核深染,大小不一。瘤组织可见黑素颗粒及坏死组织,周围有淋巴细胞浸润。免疫病理:肿瘤组织HMB45(++),S-100蛋白(++),CK(+/-)。诊断:阴茎恶性黑素瘤。
One case of penial malignant melanoma is reported. A 71-year-old male presented with black brown papules and vesicles for 3 months, with erosions and ulcers for 1 month on the caput penis. Physical examination showed lots of pitchy papules and maculopapules on the caput penis and eoronoid sulcns, with the size of grain to mung bean. There was an ulcer in the size of 0.6 x 0.6 cm on the left side of the caput penis, with nastiness, crust and secretion on the surface. Histopathology showed melanin particles anti necrotic tissue were found in the tumor tissue with lymph-cell infiltration around it. The hmnunohistoehemical examination showed HMB45（＋＋）, the S-100（＋＋） and CK（＋/-）. The diagnosis was confirmed as a penial malignant melanoma.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2012年第9期547-548,共2页
Journal of Clinical Dermatology
关键词
黑素瘤
阴茎
melanoma
penis
