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心肌型脂肪酸结合蛋白评估急性心肌梗死及再灌注的价值 被引量:3

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摘要 目的探讨心肌型脂肪酸结合蛋白(H-FABP)检测对急性心肌梗死早期诊断及评估梗死相关血管再灌注疗效的临床价值。方法胸痛6h内明确诊断急性心肌梗死患者65例,并于入院1h内接受溶栓或经皮冠状动脉介入治疗(PCI)术,入院即刻和术后3h行床边心电图检查并采血检测肌钙蛋白I(cTnI)及H-FABP,再灌注治疗后3h以心电图ST段回落≥50%为血流再通的评价指标。结果 65例AMI患者入院即刻H-FABP阳性率(87.69%)显著高于cTnI阳性率(58.46%),差异有统计学意义(P<0.05)。再灌注3h后H-FABP在ST段回降≥50%组与ST段回降<50%组中,酶峰值分别为(24.03±9.12)ng/ml与(32.57±10.25)ng/ml,差异有统计学意义(P<0.05),而cTnI测值两组比较差异无统计学意义(P>0.05)。结论 H-FABP可作为诊断急性心肌梗死的可靠标志物,也可作为评价心肌再灌注疗效的指标之一。
作者 李宁 赖登攀
出处 《心脑血管病防治》 2012年第4期297-298,共2页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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同被引文献68

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