摘要
目的了解南通地区2008～2010年泌尿生殖道感染支原体的耐药性演变,为临床提供用药指导。方法采用支原体分离培养鉴定及药敏试验试剂盒检测该院门诊患者的泌尿生殖道分泌物,回顾分析临床分离株的耐药性。结果 2008～2010年1053例标本中检测出支原体感染者527例(50.05%),女性检出率明显高于男性(P<0.01),检出率在3年中无明显改变(P>0.01)。药敏结果显示,3年中米诺环素和多西环素对支原体的敏感性较高,稳定性也较好,耐药性均低于4%;交沙霉素、克拉霉素、四环素、罗红霉素、阿奇霉素则出现了不同程度的耐药性;喹诺酮类耐药性最高,在60%以上。分析中还发现多重耐药支原体156株。结论随着抗生素的广泛使用,支原体对抗生素的耐药率越来越高,根据各地区不同的支原体流行情况及其药敏结果进行临床治疗十分重要。
Objective To detect and analyze the drug sensitivity and resistance of Mycoplasma hominis（Mh）and Ureaplasma urealyticum（Uu）in genitourinary tract infection outpatients from Nantong region and to provide evidences for the etiological diagnosis and treatment of Mycoplasma infection.Methods The Mycoplasma diagnostic kit was used for culture,identification and antibiotics sensitivity test of Mycoplasma in the samples from the outpatients.Results Out of 1 053 patients,527 patients were found to be positive for Mycoplasma infection.The detection rate for simple Mycoplasma infection in female was significantly higher than that in male（P〈0.01）.Higher sensitive rates to minomycin,doxycycline were found for both Mh and Uu,which were kept lower as 4%.Mh and Uu showed different resistance to josamycin,clatythromycine,tetracycline,roxithromycin and azithromycine.The drug resistance rate was highest to quinolones.Multiple resistance was found in 156 patients.Conclusion The drug resistance of Mycoplasma evolves with the time.Monitoring drug resistance of Mycoplasma is important for the treatment of Mycoplasma infection.
出处
《国际检验医学杂志》
CAS
2012年第12期1454-1455,1458,共3页
International Journal of Laboratory Medicine
关键词
支原体
泌尿生殖道
耐药性
Mycoplasma
genitourinary tract
drug resistance
