摘要
本实验在清肺补肾汤取得满意临床疗效的基础上,又进行了有关抗过敏性哮喘的动物实验,以探讨其疗效机理。结果表明,清肺补肾汤能有效地抑制大白鼠卵蛋白被动皮肤过敏反应,抑制豚鼠卵蛋白过敏性哮喘,拮抗组织胺和乙酰胆碱对支气管的痉挛作用,并对胸腺增殖及其免疫调节作用进行了探讨。
On the basis of satisfying clinical effects of Qingfei Bushen Decoction,the authors carried out experimental studies with animals on anti-anaphylactic asthma with the decoction (200% condensed) to probe into the effective mechanism.The experimental results showed that the condensed decoc- tion could effectively suppress rats'passive cutaneous anaphylaxis and guinea pigs'anaphylactic asthma allergized by egg protein.The results also showed that the condensed decoction obviously resisted the guinea pigs'bronchial spasm induced by histamine and acetylcholine,and it could significantly promote the multiplication of rats'thymus gland.Thymus gland multiplication and immunomodulating action are also discussed in the paper.
