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颅咽管瘤全切术后水钠平衡紊乱的治疗 被引量:131

Treatment of water and sodium disorders after complete resection of craniopharyngiomas
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摘要 目的 探讨颅咽管瘤全切术后水钠平衡紊乱的临床特点及治疗方法。方法 术前 ,手术当日及术后每日定时检测血钠及观查尿量变化并根据其变化进行治疗。结果  6 0例颅咽管瘤手术患者中 ,(1) 4 7例术后出现尿崩症 ,有 38例病人术后 2周恢复 ,7例术后 4周内恢复 ,1例术后 1年内恢复 ,1例病人术后 7天死亡。 (2 ) 5 2例术后出现血钠紊乱 ,其中 ,48例术后 4周内恢复 ,2 3例术后2个月内恢复 ,1例 1年后恢复。结论 颅咽管瘤全切术后水钠平衡紊乱情况复杂。术后尿崩症绝大多数病人均可在术后早期得到恢复。术后血钠改变多样 。 Objective To study the effective treatment of the patients with the water and blood sodium disorders after surgery. Methods The water and blood sodium in 60 patients with craniopharyngiomas resected surgically were daily observed after surgery.Results In 47 patients with diabetes insipidus, the mild diabetes insipidus was in 18 patients, moderate diabetes insipidus in 23 patients, and severe in 6 patients. 38 patients recovered in two weeks after surgery, 7 patients in four weeks, one patient recovered in one year and one patient died seven days after surgery. In 52 patients with the sodium disorder. 48 patients recovered the normal blood sodium level within 4 weeks after surgery, 3 patients recovered within 8 weeks, and one did in one year. Conclusions The water and blood sodium disorder in patients with craniopharyngiomas after surgery appears to present complicated course. The patients with diabetes insipidus were frequent after operation but most of them may recover within about 4 weeks after surgery. Treatment of the sodium disorder in the patients with craniopharyngiomas after surgery could be carried in dependence on the different characteristics of each patient.
出处 《中华神经外科杂志》 CSCD 北大核心 2000年第4期210-212,共3页 Chinese Journal of Neurosurgery
基金 国家教委留学归国人员科研基金!(99教外司留 36 3号 )
关键词 颅咽管瘤 尿崩症 术后 水钠平衡紊乱 治疗 Craniopharyngioma Diabetes insipidus Surgery
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  • 1W. S. Poon,Y. I. Lolin,T. F. Yeung,C. P. Yip,K. Y. C. Goh,M. K. Lam,C. Cockram. Water and sodium disorders following surgical excision of pituitary region tumours[J] 1996,Acta Neurochirurgica(8):921~927
  • 2T. Yamaki,A. Tano-oka,A. Takahashi,T. Imaizumi,K. Suetake,K. Hashi. Cerebral salt wasting syndrome distinct from the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)[J] 1992,Acta Neurochirurgica(3-4):156~162

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