摘要
目的:探讨无症状性脑梗死(SCI)与认知功能障碍的关系。方法:选择SCI患者101例(SCI组),70例性别、年龄、伴发慢性疾病相匹配且头颅CT/MRI检查未见梗死灶的非SCI患者为对照组(非SCI组),2组均采用蒙特利尔认知评估(MoCA)量表评估认知功能,对结果进行比较。将SCI组患者根据梗死病灶的部位、数量分为皮质组(病变位于皮质)、多发病灶组及单发病灶组(病变均位于非皮质部位),对3个亚组的评分进行比较。结果:SCI组患者的认知功能障碍发生率(53.5%)显著高于非SCI组(21.4%,P<0.01);SCI组中皮质组脑梗死患者的认知功能障碍程度重于非皮质部位的多发及单发病灶组患者;多发病灶组患者的认知功能障碍程度重于单发病灶组。结论:SCI可造成认知功能障碍;梗死的部位、梗死病灶的数量均与认知功能障碍的程度相关。
Objective：To explore the relationship between the silent cerebral infarction（SCI）and cognitive dysfunction.Methods：Choosing 101 patients with SCI（SCI group）and 70 patients matching in sex,age,chronic disease,and not seeing the infarcts by brain CT/MRI as control group（non-SCI group）.All of two groups used Montreal cognitive assessment（MoCA）scale to evaluate cognitive function,the results were compared.According to the number and place of infarction.Patients of SCI group were divided into cortex group（lesions in the cortex）,multiple lesion group and a single lesion group（lesions were not in the cortex parts）,three groups were compared according to the score.Results：Cognitive dysfunction rate of SCI patients（28.7%）was higher than the non SCI group（8.6%）.In SCI group,cortical group of patients with cerebral infarction cognitive dysfunction was more serious than the single and multiple lesions in non-cortical parts.Multiple lesion group of patients with cognitive function was more serious than a single lesion group of patients.Conclusion：SCI can cause cognitive dysfunction.The positions and the numbers of infarctions are related to the cognitive dysfunction degree.
出处
《中日友好医院学报》
2012年第4期221-223,共3页
Journal of China-Japan Friendship Hospital
基金
辽宁省科技厅科技攻关计划项目2011225020号
关键词
无症状性脑梗死
认知功能障碍
蒙特利尔认知评估量表
silent cerebral infarction； cognitive dysfunction； Montreal cognitive assessment scale
