摘要
目的:研究玄参破壁粉粒的抗炎作用,并进行急毒实验。方法:抗炎作用采用小鼠急性耳肿胀实验。急毒实验测定玄参破壁粉粒对小鼠的最大给药量。结果:玄参破壁粉粒能抑制小鼠耳廓肿胀度。等剂量下,玄参破壁粉粒的抗炎作用强于常规饮片。测得小鼠最大给药量为20 g/kg,相当于成人临床同体重日用量的100倍。结论:玄参破壁粉粒具有抗炎作用。玄参破壁粉粒及其常规饮片具有相同的安全性。
Objective：To investigate the anti-inflammatory effect of Radix Scrophulariae Particle,and to carry out an acute toxicity test.Methods：The acute swelling of ear test and maximum dosage test were performed in the experiment.Results：Radix Scrophulariae Particle could significantly inhibit inflammation.Drug action of isodose Radix Scrophulariae Particle is better than isodose cut crude drug of Radix Scrophulariae.The mouse maximum dosage is 20 g/kg,which is 100 times adult daily dosage.Conclusion：Radix Scrophulariae Particle possessed anti-inflammatory effect.The safety of Radix Scrophulariae Particle is same with cut crude drug of Radix Scrophulariae.
出处
《江西中医学院学报》
2012年第1期52-54,共3页
Journal of Jiangxi College of Traditional Chinese Medicine
基金
2008年粤港关键领域重点突破项目(200801)
关键词
玄参破壁粉粒
抗炎
急毒
Radix Scrophulariae Particle； Anti-inflammatory effect； Acute toxicity test；
