摘要
报告本室近年研究松果体分泌的神经体液调节和神经支配的主要成绩。通过一系列动物实验探讨松果体对应激反应存在昼夜差别的原因。通过电镜等方法证明交感神经对松果体细胞有营养功能;有大量来自中枢的有髓和无髓纤维经缰核和后连合进入深部松果体;一些内含大颗粒泡的无髓纤维终末与含清亮泡的神经终末在松果体内有突触性联系;松果体细胞具有接触脑脊液的形态学基础。通过切除睾丸和注射睾酮的实验,用形态定量分析的方法,说明幼年大鼠的睾丸分泌物对松果体的功能有抑制作用,但过量的睾酮不会增加此种抑制。
This paper reviews our last several year's studies on neurohumoral regulation and in-nervation of the pineal gland. Through a series of animal experiments, the mechanism of the difference of the rat pineal response to swimming stress between during the day and at night was investigated. Using the EM and other methods we have demonstrated that the sympathetic nerve had the nutritious function to pinealocytes, a lot of myelinated and un-myelinated central nervous fibers coming through the habenula and the posterior commissure reached the deep pineal gland, some unmyelinated nerve endings containing large dense-core vesicles contacted the nerve endings containing small clear vesicles with synaptic complexes in pineal gland, many morphological signs suggested that pinealocytes had the possibility to contact CSF. In rats which were orchiectomized or injected subcutaneously testosterone every afternoon for 35 days, we had showed with morphometry that the testis secretion of young male rats had- inhibitive effect on pinealocytes, but overdose administration of testosterone could not enhance this inhibitive effect significantly.
出处
《中山医科大学学报》
CSCD
1990年第4期1-3,共3页
Academic Journal of Sun Yat-sen University of Medical Sciences
基金
国家教委博士点基金
关键词
松果体
睾酮
松果体隐窝
应激反应
Pineal gland Pineal recess Stress Melatonin Testosterone
