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麝香保心丸对急性冠脉综合征患者氯吡格雷抵抗的影响 被引量:4

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摘要 目的:评价麝香保心丸对急性冠脉综合征(ACS)患者氯吡格雷抵抗(CR)的影响。方法:选择氯吡格雷抵抗患者64例,将其随机分为两组。A组34例,口服氯吡格雷75mg,同时加用麝香保心丸4粒/次,每日3次。B组30例,每日口服氯吡格雷75mg。C组为无氯吡格雷抵抗患者35例,每日口服氯吡格雷75mg。于服氯吡格雷前、服药后2周分别测定血小板聚集率抑制率。结果:3组患者在服用氯吡格雷前血小板聚集率无统计学意义(P>0.05),服药1周后,血小板聚集率A组为(21.5±3.9)%,B组为(28.1±5.7)%,C组为(17.9±4.7)%;血小板抑制率A组为(10.2±2.5)%,B组为(8.8±1.8)%,C组为(14.6±2.3),与治疗前比较有统计学意义(P<0.05)。其中,血小板聚集率C组<A组<C组,血小板抑制率C组>A组>B组(P<0.05)。结论:麝香保心丸可以降低ACS患者发生氯吡格雷抵抗的几率。
作者 张景 吕云波
出处 《求医问药(下半月刊)》 2012年第6期91-92,共2页 Seek Medical and Ask The Medicine
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