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右美托咪啶用于腰硬联合麻醉的临床观察 被引量:10

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摘要 目的观察右美托咪啶用于下腰部手术中的安全性和有效性。方法将ASAⅠ或Ⅱ级拟行腰硬联合麻醉(CSEA)的患者60例随机均分为右美托咪啶组(D组)、咪唑安定组(M组)和生理盐水对照组(N组)。D组和M组于腰硬联合麻醉成功后手术开始前10 min分别静脉注射右美托咪啶0.6μg/kg和咪唑安定0.6 mg/kg(泵注时间为10 min),分别以0.6μg(/kg.h)和0.6 mg(/kg.h)的速度维持。结果 D组、M组患者Ramsay评分显著高于N组(P<0.01),术后24 h随访顺行遗忘程度高于N组。结论静注右美托咪啶0.6μg/kg后以0.6μg(/kg.h)的速度持续输注适合于CSEA的镇静。
机构地区 天镇县人民医院
出处 《基层医学论坛》 2012年第23期3036-3037,共2页 The Medical Forum
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