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羟丁酸钠对沙土鼠脑缺血再灌注损伤的保护作用 被引量：6

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摘要 目的　观察羟丁酸钠 (γ -OH)对脑缺血再灌注损伤的保护作用。方法　采用沙土鼠双侧颈总动脉结扎法制作前脑缺血再灌注损伤的模型 ,观察γ -OH对脑缺血沙土鼠行为学和病理学的影响。结果　γ -OH能明显降低脑缺血再灌注沙土鼠的定向运动活性 ,减轻海马CA1区锥体细胞的损害。结论　γ
作者 张晶 郭继东 谷淑玲 戴体俊
机构地区 徐州医学院药理学教研室 徐州医学院麻醉药理学教研室
出处 《徐州医学院学报》 CAS 2000年第2期107-109,共3页 Acta Academiae Medicinae Xuzhou
关键词 羟丁酸钠 脑缺血 再灌注损伤 沙土鼠
分类号 R743.310.2 [医药卫生—神经病学与精神病学] R971.2 [医药卫生—药品]
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二级参考文献27

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共引文献41

同被引文献27

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引证文献6

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徐州医学院学报
2000年 第2期

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