摘要
目的 观察眼内不同部位移植视网膜神经上皮层后诱发的免疫排斥 /赦免反应。方法 将新生小鼠视网膜神经上皮层分离后移植到受鼠眼结膜下、玻璃体腔和视网膜下间隙 ,术后 2、6、12、18、35 d用光镜观察移植物的存活 /排斥情况。结果 位于结膜下移植物 2 d内发生排斥反应 ,而位于玻璃体腔和视网膜下间隙的移植物不仅未被排斥 ,而且能进一步生长发育。
Objective To observe the immune rejection/privilege reaction by neonatal neural retina grafting in different sites of the eye.Method Separate the neonatal neural retinae then transfer them to subconjunctival space (SCon),vitreous cavity (VC) and subretinal space.The conditions of grafts survival/rejection were observed on 2nd,6th,12th,18th,and 35th day after the operation by light microscopy.Result The data showed that grafts in VC and subretinal space not only averted themselves from any rejection but also attained further development.Conclusion The vitreous cavity and subretinal space are of immune privilege.
出处
《山西医药杂志》
CAS
2000年第2期114-115,共2页
Shanxi Medical Journal
