摘要
为了预测生物组织低温保存过程中所受到的机械损伤 ,建立了一维球对称模型 ,模拟计算了降温过程相变界面随时间的移动 ,壁面温度随时间的变化 ;组织内温度分布不均引起的热应力随时间变化及其在壁面的分布。主要考虑了降温速率的影响 ,当降温速率低于某一值时 ,降温速率越高 ,组织内部所受热应力越大 ;降温速率超出这个值 。
The aim of this study was to predict the cryoinjury that was caused by thermal stresses during cryopreservation of living cells, tissues and organs. A thermal stress analysis model is developed for water freezing processes taking place inside a ball. The model allows us to predict the temperature field, moving phase interface location and the thermal stress distributions in the ice. A quick freezing process results in larger thermal stresses in the ice than a slow freezing process does within a certain level. Above this level, the freezing rate has no effect on the thermal stresses.
出处
《真空与低温》
2000年第2期98-103,共6页
Vacuum and Cryogenics
基金
国家自然科学基金重点资助项目!(59836240)
