摘要
目的 :研究狼疮性肾炎 (LN)患者血清酶的变化及临床意义。方法 :通过全自动生化分析仪检验 34例LN患者及 30名健康体检者血中 8种血清酶。结果 :LN组较健康组LDH、HBDH、AST、GGT(P <0 0 1)、ALP(P <0 0 5 )明显升高 ,均有显著性意义 ,而CK、AMY和ALT(P >0 0 5 )无显著性意义。LDH和HBDH(P <0 0 0 0 5 )之间有高度相关性。结论 :LDH、HBDH、AST、GGT和ALP可能为诊断LN有实用价值的指标。LDH在肾脏含量丰富 ,而且灵敏性高 ,HBDH较LDH特异性高 ,互为补充 。
Objective: To study the clinical implication of seroenzyme changes in patient with lupus nephritis (LN). Methods: Eight serum enzymes of 34 patients with LN and 30 normal persons were examined by automatic biochemical analyzer. Results: Compared with normal person, the serum levels of LDH, HBDH, GOT, GGTP and ALP were significantly increased and CK, AMY and ALT had no significant difference in patients with LN. This trial showed that LDH had a strong positive correlation with HBDH. Conclusion: Elevation of the serum LDH, HBDH,GOT, GGTP and ALP levels may be used as a better diagnosis predictor for LN. Among all organs, the kidney is the richest in LDH content. The LDH is highly sensitive and the HBDH is the most specific. Both LDH and HBDH can increase diagnostic reliability of LN.
出处
《宁夏医学院学报》
2000年第3期170-171,174,共3页
Journal of Ningxia Medical College
