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从内疫谈抗中性粒细胞胞浆抗体相关性血管炎的发病与治疗 被引量:5

On the Pathogenesis and Treatment of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis from the Aspect of Internal Epidemic
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摘要 目的:从内疫探讨抗中性粒细胞胞浆抗体(ANCA)相关性血管炎(AASV)的发病与治疗。方法:从人体杂气与内疫、人体杂气与AASV发病以及人体杂气与AASV治疗的相关性出发,对ANCA相关性血管炎的发病与治疗进行阐述。结果:正气亏虚是导致内疫病机的直接病因,可将AASV的发生归咎于人体自身杂气的失制。治疗采用扶正与攻毒联合用药,攻补并施,形成促使变逆之气向正气转化的合力,实现扶正与攻毒两种治法在针对病机上的矛盾统一。结论:通过对AASV的内疫病机讨论,为继承及使用杂气病因学说治疗AASV提供了可能,以期为AASV的中医治疗提供新的思路。 Objective: To explore the incidence and treatment of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AASV) from the aspect of internal epidemic. Methods:The incidence and treatment of anti-neutrophil cytoplasmic antibody (ANCA) associated vaseulitis(AASV) was described from the relevances of the body internal epidemic and miscellaneous epidemic factors,the body internal epidemic and the incidence of AASV as well as the body internal epidemic and treatment of AASV. Results:The deficiency of healthy qi was the direct cause that resulted in the pathogenesis of epidemic, and the occurrence of AASV could be attributed to the disharmony of the body's own miscellaneous epidemic factors. The treatment adopted the combination therapy of supporting the healthy qi and removing the toxic factors. The simultaneous treatment of reinforcing and purging could facilitate the formation of the joint force of changing the reversing qi into healthy qi in order to achieve the unity of the conflicts of using two treatment methods of supporting the healthy qi and removing the toxic factors aiming at the pathogenesis. Conclusion:The discussion of the pathogenesis of internal epidemic of AASV offers the possibility to inherit and use of the theory of miscellaneous epidemic factors and etiology for the treatment of AASV in order to provide new ideas for the Chinese medicine treatment of AASV.
作者 梁晖 林书洲
机构地区 广东省中医院
出处 《中医学报》 CAS 2012年第8期969-970,共2页 Acta Chinese Medicine
基金 广东省科技计划项目(编号:2010B030700062)
关键词 内疫 杂气 抗中性粒细胞胞浆抗体相关性血管炎 扶正 攻毒 温病学 internal epidemic miscellaneous epidemic factors anti-neutrophil cytoplasmic antibody-associated vasculitis supporting thehealthy qi removing the toxic factors doctrine of epidemic febrile diseases
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  • 1Lane S E, Watts R A, Bentham G, et al. Areenvironmental factors im- portant in primary systemic vasculitis [ J ]. Arthritis Rheum, 2003,48 (3) :814 -823.
  • 2Haubitz M,Woywodt A,Greot K,et al. Smoking habits in patients di- agnosed with ANCA associated small vessel vasculitis[ J]. AnnRheum Dis,2005,64(10) :1500 - 1502.
  • 3Schreiber A, Busjabn A, Luft F C, et al. Membrane expression of pro- teinase 3 is genetically determined[ J]. J Am Soc Nephrol,2003,14 ( 1 ) :68 - 75.

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