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雄激素及其受体与膀胱癌的研究进展

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摘要 膀胱癌是泌尿外科最常见的肿瘤,也是性别差异较大的肿瘤之一,男性恶性肿瘤中列第四位,女性列第六位,男性发病率是女性的3.5倍[1]。早在几十年前就有学者发现膀胱癌组织中存在性激素受体,并提出除了吸烟和化学致癌物等环境因素外,性激素的影响可能与这种性别差异有关,并且可能在膀胱癌的发生、发展中发挥一定作用[2]。在性激素中,雄激素及其受体（AR）对膀胱癌的作用较引人注目,
作者 黄斌 关琳琳 丘少鹏
机构地区 中山大学附属第一医院泌尿外科 中山大学中山医学院微生物教研室
出处 《现代泌尿生殖肿瘤杂志》 2012年第3期185-186,共2页 Journal of Contemporary Urologic and Reproductive Oncology
关键词 性激素受体 膀胱癌组织 雄激素 恶性肿瘤 性别差异 化学致癌物 泌尿外科 环境因素
分类号 R737.14 [医药卫生—肿瘤]
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参考文献19

  • 1Colombel M, Soloway M, Akaza H, et al. Epidemiology, staging, grading, and risk strati{ication of bladder cancer[J]. Eur Urol Suppl,2008,7(10) :618-626.
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二级参考文献24

  • 1苏勤.妇科肿瘤分子病理研究进展的启示[J].中华病理学杂志,2003,32(4):305-307. 被引量：6
  • 2刁小莉,苏勤,王淑芳,张伟,巩丽,刘节,冯英明.子宫平滑肌瘤不同结节X染色体失活类型的研究[J].中华病理学杂志,2003,32(4):308-313. 被引量：10
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现代泌尿生殖肿瘤杂志
2012年 第3期

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