摘要
目的:探讨大规模人群癌症早期普查对研究自然发病趋势变化的影响。方法:利用肿瘤登记处统计的肿瘤发病资料。抽样两个乡镇(驸马沟、固义乡)1998-2008年间食管癌发病率情况,计算发病粗率进行描述分析,对产生趋势变化原因予以讨论。结果:1998-2003年间驸马沟乡的食管癌发病率波动在75-149/10万之间,2005年发病率陡然升高至350.17/10万,超出历年发病最高水平的2.4倍多。固义乡的发病趋势情况亦类似,只是发病最高在2006年,为263.57/10万。次年,发病率急剧下降至61.50/10万。两年发病波动较大。结论:2005-2006年间,曾对这两个乡镇进行了大范围食管内镜早期普查干预。因人为干预而造成该时间段食管癌趋势陡然升高,从而对短期时间分析趋势变化造成影响。普查提前检出的癌症患者在进行人群肿瘤登记中,应做好标注统计,杜绝或减少各种偏倚,为综合评价癌症普查效果奠定基础。
Objective：To investigate the large - scale screening of natural populations of cancer incidence trends change. Methods ： Using tumor registry information on cancer incidence statistics, sampling two townships （ FU MA GOU, GU YI XIANG） 1998 -2008 years, the incidence of esophageal cancer calculated to describe the incidence, give the reasons for the change in trend. Results ：1998 -2003 FU MA GOU Township, fluctuations in the incidence of esophageal cancer among the 75 - 149/10 million in 2005, the incidence increased steeply to 350.17/10 million, exceeding historical incidence of the highest level of 2.4 times. GU YI trends was similar, but the highest incidence in 2006, was 263.57/100000. The following year, the incidence rate dropped dramatically to 61.50/10 million. Conclusion ： The reasons for changes caused by short - term trends for 2005 to 2006 years, in these two towns, large - scale screening of esophageal endoscopic intervention were carried out. A result of human intervention in the time trend of sharp increase in esophageal cancer arm thus changes in short time impact of trends. Screening for early de- tection of cancer tumors in patients during the registration should be well marked, to eliminate or reduce all kinds of bias, for a comprehensive evaluation of cancer screening results.
出处
《现代肿瘤医学》
CAS
2012年第8期1711-1713,共3页
Journal of Modern Oncology
关键词
食管癌
普查
发病率
趋势
esophageal cancer
screening
incidence rate
trends
