摘要
目的:采用随机对照试验研究,观察艽龙胶囊治疗肝胃郁热型癌性腹胀的临床疗效及安全性。方法:以确诊为盆腹腔原发或转移晚期肿瘤并发肝胃郁热型癌性腹胀的门诊病例为观察对象,入组50例,随机分2组,治疗组,对照组各25例。治疗组用艽龙胶囊2粒/次,每日3次,餐前半小时服用。对照组用胃复安2粒10mg/次,每日3次,餐前半小时服用。两组疗程均为28天。结果:治疗组25人,临床治愈1人,显效9人,有效14人,无效1人,总有效率96%;对照组25人,临床痊愈0人,显效5人,有效8人,无效12人,总有效率52%,差异有统计学意义(P<0.01)。两组治疗后症状积分均有下降,组间比较差异均有统计学意义(P<0.05)。结论:艽龙胶囊治疗肝胃郁热型癌性腹胀有较好的临床疗效,对患者的胃脘饱胀、口苦口干、便秘等主要症状有明显改善作用,无明显不良反应,安全性较好。
Objective：To observe the effect and safety of jiaolong capsule on treating cancer induced abdominal distension. Methods：All 50 patients with abdominopelvic cavity cancer and cancer - induced abdominal distension （Zheng of Hepatogastric YuRe） were divided into two groups randomly, 25 in each group. Patients in treatment group took jiaolong capsule half an hour before dining （ two pills every time, and three times per day）, while the control group using Metoclopramide. The period of treatment in each group was 28 days. Results ：There were 1 case cured, 9 cases were significantly improved, 14 cases were in effect and I case were non - effective among 25 cases in treatment group, and the total effective rate was 96%. There were 0 case cured, 5 cases were significantly improved, 8 cases were in effect and 12 cases were non -effective in control group, the total effective rate was 52%. There was signifi- cant difference between two group （P 〈 0.01 ） , the syndrome integral of two groups decreased after the treatment and there was statistically significant difference between two groups （P 〈 0.05 ）. Conclusion ： It has better clinical efficacy by using the method of jiaolong caspule in treating cancer - induced abdominal distension （ Zheng of Hepatogastric YuRe） , and it has significantly improved role in patients which have the major symptoms such as distention,dry mouth,etc. Jiaolong capsule has no obvious side effect on treating cancer- induced abdominal distensiorL It is safe, effective.
出处
《现代肿瘤医学》
CAS
2012年第8期1706-1708,共3页
Journal of Modern Oncology
关键词
癌性腹胀
肝胃郁热
艽龙胶囊
cancer induced abdominal distension
Zheng of Hepatogastric YuRe
Jiaolong capsule
