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珂立苏治疗新生儿呼吸窘迫综合征135例临床分析 被引量:6

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摘要 目的:探讨肺表面活性物质(珂立苏)治疗新生儿呼吸窘迫综合征(NRDS)的疗效。方法:回顾性分析新生儿诊治中心2008年1月~2009年10月收治的135例NRDS患儿,分析并比较珂立苏使用前,使用后1、6、12 h血气指标、呼吸机参数、胸片变化及并发症发生情况。结果:135例患儿用药前后血气指标及呼吸机参数比较差异有统计学意义,最高吸气末峰压(PIP)、呼气末正压(PEEP)、平均气道压(MAP)及FiO2(吸入氧浓度)在使用珂立苏治疗后均呈下降趋势(P<0.05),NRDS患儿pH及PO2明显升高,PCO2明显降低(P<0.05)。使用珂立苏后发生肺出血4例,占2.36%;气胸6例,占4.24%。结论:珂立苏可明显改善肺的氧合情况,迅速改善新生儿缺氧及酸中毒。
出处 《中国妇幼保健》 CAS 北大核心 2012年第20期3215-3216,共2页 Maternal and Child Health Care of China
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