摘要
目的探讨间断性肾脏替代治疗(IRRT)对重症急性胰腺炎(SAP)的临床疗效。方法分析我科自2008年10月~2011年11月21例SAP患者行间断血液滤过治疗的疗效。观察治疗前后患者的体温、心率、呼吸、血压,检测肝肾功能、氧合指数(PO2/FiO2)、电解质、葡萄糖、血常规,并行APACHEⅡ评分。结果 21例SAP患者存活18例,死亡3例;经IRRT治疗后APACHEⅡ评分明显下降(P<0.05),生命体征明显好转;生化指标明显改善(P<0.05)。结论常规综合治疗SAP同时,早期合理应用IRRT可以清除炎症介质,维持内环境稳定,改善脏器功能,提高疗效,为临床治疗SAP提供一种重要辅助手段。
Objective To investigate the clinical effect of intermittent renal replacement therapy(IRRT)on severe acute panreatitis(SAP).Methods A total of 21 patients with SAP were received IRRT from Oct 2008 to Nov 2011,and the clinical data were retrospectively analyzed including the indications and related biochemical indicators in early stages(2-3 days).Results The signs of life,blood electrolytes,liver and renal function in biochemical indices and abdominal pain inflation and other symptoms were improved in the patients underwent IRRT.The scores of APACHEⅡwere apparently decreased.In these 21 patients,18 cases were cured,3 dead of multiple organs dysfunction syndrome.Conclusion IRRT treatment can keep stability of inner environment and the organ function in treatment of SAP.
作者
叶华
何清
曾丽萍
钟贵芳
郭瑞莲
Ye Hua;He Qing;Zeng Liping;Zhong Guifang;Guo Ruilan(Department of Intensive Care Unit,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120)
出处
《岭南现代临床外科》
2012年第4期324-326,共3页
Lingnan Modern Clinics in Surgery
关键词
血液滤过
间断性肾脏替代治疗
连续性肾脏替代治疗
重症急性胰腺炎
Hemofiltration(HF)
Intermittent renal replacement therapy
Continous renal replacement therapy
Severe acute panreatitis
