摘要
目的采用动态磁敏感对比MR灌注加权成像(DSC-PWI)评估脑梗死后交叉性小脑机能联系不能(CCD)的发生因素及机制。方法对81例确诊为单侧幕上脑梗死患者行DSC-PWI和MR常规检查,记录大脑半球不对称指数(AIcbⅠ)、小脑不对称指数(AIcbⅡ)、幕上脑梗死体积、梗死位置、患者是否有偏瘫及活动受限的情况。将患者分为CCD阳性组和CCD阴性组,比较两组相关参数的差异,分析CCD阳性患者幕上梗死参数与AIcbⅡ之间的相关性。结果 CCD阳性组35例(43.21%),在梗死时间、梗死部位、偏瘫及活动受限情况方面与CCD阴性组的差异有统计学意义(P均<0.05)。CCD阳性组患者幕上梗死体积和AIcbⅡ之间呈正相关(r=0.25,P=0.01),梗死持续时间与AIcbⅡ之间无相关性(r=0.19,P=0.59)。结论 CCD可能是皮层脑桥小脑通路中断的结果,其发生可能与梗死时间、梗死部位、患者偏瘫及活动受限情况有关。
Objective To observe the impact factors and mechanisms of crossed-cerebellar diaschisis（CCD） after cerebral infarction with dynamic susceptibility contrast-perfusion weighted imaging（DSC-PWI）.Methods DSC-PWI and conventional MR scans were performed in 81patients with hemi-supratentorial cerebral infarction.Cerebral asymmetry index（AI cbⅠ）,cerebellar asymmetry index（AI cbⅡ）,volume of supratentorial infarction,location of infarction,hemiplegic paralysis or not and limitation of activity were recorded.The patients were divided into two groups according to CCD and were compared,the correlation between parameters in supratentorial infarction and AI cbⅡ of patients with CCD were analyzed.Results The occurrence rate of CCD was 43.21%（35 / 81）.There were statistical differences between two groups in time and location of infarction,information of hemiplegic paralysis and limitation of activity（all P〈0.05）.There was positive correlation between volume of supratentorial infarction and AI cbⅡ（r=0.25,P=0.01）,while persistence time of infarction showed no significant correlation with the AI cbⅡ（r=0.19,P=0.59）.Conclusion CCD may be a consequence of disrupted cortico-ponto-cerebellar pathway,which is related to time and location of infarction,information of hemiplegic paralysis and limitation of activity.
出处
《中国医学影像技术》
CSCD
北大核心
2012年第7期1268-1271,共4页
Chinese Journal of Medical Imaging Technology
关键词
灌注成像
磁共振成像
脑梗死
交叉性小脑机能联系不能
Perfusion imaging
Magnetic resonance imaging
Cerebral infarctiom Crossed-cerebellar diaschisis
