摘要
目的探讨血清视黄醇结合蛋白(Retinol-binding protein RBP)测定对鉴别肝硬化及胃十二指肠溃疡并发上消化道出血的临床意义。方法采用免疫透射比浊法检测44例肝硬化并发上消化道出血、58例胃十二指肠溃疡并发上消化道出血和51名健康成年人血清RBP的含量,并进行相关统计分析。结果肝硬化并发上消化道出血组患者血清RBP含量显著低于正常对照组及胃十二指肠溃疡组(P<0.01);胃十二指肠溃疡组与正常对照组患者血清RBP的含量(P>0.05)差异无统计学意义。结论血清RBP能及时的反映肝脏损伤情况及肝脏的合成代谢功能,可作为鉴别肝硬化和胃十二指肠溃疡并发上消化道出血的一种简单有效的方法,对患者的治疗提供一定的临床参考价值,值得临床医生关注。
Objective To investigate the clinical significance of serum retinol-binding protein（RBP） in the diagnosis of liver cirrhosis and gastroduodenal ulcer complicated by hemorrhage of upper digestive tract.Methods The serum RBP concentration was detected by immunoturbidimetry and the statistical analysis was performed in the 44 cases of liver cirrhosis combined with upper gastrointestinal hemorrhage,58 cases of the gastroduodenal ulcer complicated with upper gastrointestinal hemorrhage and 51 healthy adults＇ serum RBP content.Results There was statistical significance in the serum RBP concentration,in liver cirrhosis group,RBP was lower than that in the control group and the gastroduodenal ulcer group（P0.01）.There was not statistical significance in the serum RBP concentration between the gastric and duodenal ulcer group and normal control group（P﹥0.05）.Conclusion Serum RBP can timely reflect the liver damage and the anabolic function of the live,it was simply and effective to discriminate hemorrhage of liver cirrhosis and gastroduodenal ulcer by determining serum retinol-binding protein,helpful to the treatment of patients with certain clinical reference value,worth of clinician concerns.
出处
《中华全科医学》
2012年第8期1204-1205,共2页
Chinese Journal of General Practice
关键词
视黄醇结合蛋白
胃十二指肠溃疡
肝硬化
上消化道出血
Retinol-binding protein
Gastroduodenal ulcer
Liver cirrhosis
Upper gastrointestinal hemorrhage
