摘要
目的探讨维生素K1注射液致不良反应的一般规律特点,为临床合理用药提供参考。方法检索中国期刊全文数据库,对2011年12月31日之前国内公开发表文献中,有关维生素K1注射液致不良反应146例个案报道进行回顾性分析。结果维生素K1注射液发生的不良反应可能与药物因素、患者自身因素、临床使用因素相关。结论临床应合理使用维生素K1注射液,重视药物不良反应的临床监测,确保用药安全。
Objective We probe into the status, characteristics and influencing factors of ADR cases induced by vitamin-K1 injection, for providing a reference for clinical treatment. Methods Date were collected from domestic published literatures from ＂China Journal Full-text Database＂ before December 31, 2011 and 146 case reports of adverse drug reactiom induced by vitamin-K1 injection were analyzed retrospectively. Results Adverse drug reactions induced by vitamin-K1 injection may be related to pharmaceutical factors, patients＂ factors and clinical using factors. Conclusion Vitamin-K1 injection should be used reasonably and attach importance to monitoring of clinical to ensure the safety of medication.
出处
《中国药物警戒》
2012年第7期427-430,共4页
Chinese Journal of Pharmacovigilance
关键词
维生素K1注射液
不良反应
文献分析
vitamin-K1 injection
adverse drug Reactions
literature analysis
