摘要
目的:探讨测定血浆C反应蛋白(CRP)和D-二聚体水平在冠心病急性心肌梗死(AMI)心脏破裂患者中的临床意义。方法:观察50例AMI心脏破裂(心室游离壁破裂)患者血浆CRP和D-二聚体水平,并与50例AMI但未发生心脏破裂的患者进行对照比较。结果:心脏破裂患者组(实验组)CRP和D-二聚体水平较未破裂组(对照组)明显升高,CRP和D-二聚体水平高低与心脏破裂的发生率呈正相关(P<0.05)。从风险比看,高CRP患者的破裂风险是低的4.125倍,高D-二聚体患者的破裂风险是低的2.471倍。结论:AMI患者的血浆CRP和D-二聚体水平,作为一种敏感性指标,对预测心肌梗死患者发生心脏破裂有一定的价值。
Objective：To investigate the clinical significance of detecting C-reactive protein （CRP） and D-dimer in patients with cardiac rupture after acute myocardial infarction （AMI）. Methods：Serum levels of CRP and D-dimer were observed in 50 patients with cardiac rupture after AMI, and compared with those of 50 AMI patients without cardiac rupture. Results ： Serum levels of CRP and D-dimer were significantly elevated in patients with cardiac rupture （ experimental group） than those without cardiac ruptured （ control group）. Serum levels of CRP and D-dimer were positively related with the inci- dence of cardiac rupture （ P 〈 0.05 ）. The risk of cardiac rupture in patients with high CRP was 4. 125 times than those with low CRP,and high D-dimer was 2. 471 times than those with low D-dimer level. Conclusions：As a sensitive index, serum levels of CRP and D-dimer may predict the incidence of the cardiac rupture in patients with AMI.
出处
《内科急危重症杂志》
2012年第3期151-152,158,共3页
Journal of Critical Care In Internal Medicine
