摘要
目的探讨永存左上腔静脉与胎儿畸形的关系及永存左上腔静脉的产前诊断价值。方法在我院行产前系统超声检查的7721例孕妇,以永存左上腔静脉胎儿为研究对象,超声检查胎儿生长径线和脏器结构,并随访结果。结果产前超声共发现永存左上腔静脉胎儿47例。41例经产后证实,6例失访。产后证实心脏畸形27例(65.9%),其中18例(43.9%)合并内脏异位,为内脏异位综合征,7例(17.1%)单纯心脏畸形,2例(4.9%)合并染色体畸形;5例(12.2%)单纯心外畸形;9例(22.0%)单纯PLSVC。胎儿畸形总发生率78.0%(32/41)。结论永存左上腔静脉胎儿常合并内脏异位畸形以及其他心内、心外畸形,永存左上腔静脉与胎儿畸形有密切的关系,是产前超声筛查胎儿畸形的有效标志,产前诊断永存左上腔静脉有重要的价值。
Objective ： To investigate the relationship between the persistent left superior vena cava （PLSVC） and fetal defects, the clinical significance of assessment of PLSVC in fetal screening. Method： 7721 fetuses from our hospital were scanned and the fetuses with PLSVC were included. Parameters of fetal growth and anatomical survey were detected. Results： Forty - seven cases with PI_SVC were detected prenatally. Forty - one cases were confirmed postnatally. Heart defects were found in 27 （65.9%） of these cases. Among them, 18 （43.9%） had heterotaxy syndrome, 7 （ 17. 1% ） had isolate heart defects, 2 （4. 9% ） had chromosomal defects. Isolated extracadiae anomalies were found in 5 （ 12. 2% ） cases. The remaining 9 （22.0%） had no associated condition. Fetal malformations were present in 32 （78.0%） of these cases. Conclusions ： PLSVC detected in fetal life is frequently associated with heterotaxy syndromes, other cardiac and extracadiac malformations. It is closely related to fetal defects, and can be used as effective indicator in screening fetal defects. There is an important clinical significance of assessment of PLSVC in fetal screening.
出处
《中国优生与遗传杂志》
2012年第7期100-101,121,共3页
Chinese Journal of Birth Health & Heredity
关键词
超声检查
产前诊断
永存左上腔静脉
Uhrasonography
Prenatal diagnosis
Persistent left superior vena Cava
