摘要
目的 研究 2型糖尿病患者微量白蛋白尿与动态血压、胰岛素水平之间的关系。方法 5 0例 2型糖尿病患者分成微量白蛋白尿组 (2 3例 )和正常白蛋白尿组 (2 7例 ) ,分别测 2 4h动态血压、HbA1c、胆固醇、甘油三酯、血浆胰岛素水平。结果 ①微量白蛋白尿组的夜间收缩压、平均动脉压分别为 18.90± 0 .91kPa和 12 .94± 0 .12kPa ,较正常组 16 .30± 0 .81kPa和 11.83± 0 .6 9kPa明显升高 (P <0 .0 5 )。②微量白蛋白尿组血浆胰岛素水平明显高于正常组 (P >0 .0 5 )。而血脂、血糖、HbA1c两组无显著差异 (P >0 .0 5 )。结论 2型糖尿病患者微量白蛋尿与夜间收缩压。
objetive To evaluate the relationship between microalbuminuria and 24h ambulatory blood pressure or the plasma concentration of insulin type 2 diabetes mellitus.Methods Fifty patients were divided into two groups:one group (23 cases)of microabluminuria and the group (27 cases)of normal abluminuria as the control.The twenty four hours ambulatory blood pressure,the plasma concentration of HbA 1c ,triglyceride,total cholerberol,glucos and insulin were measured.Results Nocturnal systemic blood pressure(18.90±0.91kPa)and mean arterial pressure(MAP)(12.94± 0.12 kPa)were significantly higher than that in the microalbuminuria group and in the control group( 16.30 ± 0.81 kPa,11.83±0.69kPa)respectively.The plasma concentration of insulin was remarkably higher in the microalbuminuria group than that in the control( P <0.05).There was no difference in TG,Chol,FBG and HbA 1c between two groups.Conclusion There is close correlation between microalbuminuria and nocturnal SBP,MAP and the concentration of insulin in patients with type 2 diabetes mellitus.
出处
《苏州医学院学报》
2000年第4期351-352,共2页
Acta Academiae Medicinae Suzhou
关键词
Ⅱ型糖尿病
微量白蛋白尿
动脉血压
胰岛素
type 2 diabetes mellitus
microalbuminuria
ambulartory blood pressure
insulin
