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室性心律失常与QT离散度的相关研究

A study of QT dispersion in patients with ventricular arrhythmias
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摘要 目的 :评价QT离散度 (QTd)与临床室性心律失常级别之间的关系 ,探讨影响室性心律失常QTd的因素及其临床意义。方法 :前瞻性研究 10 0例室性心律失常病例 ,测量体表同步十二导联心电图的QTd等值 ,及随病情的变化。结果 :Lown氏Ⅲ级以上病例 (35例 )与Lown氏Ⅲ级以下 (6 5例 )相比 ,QTd、QTcd、QTc显著增大。 40对配对病例QT离散度logistic多元回归分析发现室性心律失常级别与体表ST -T改变对QTd影响最显著。 8例心源性昏厥病例较 7例非心源性昏厥病例QTd、QTcd显著增大。 40例病人二次记录QTd差异与正常对照相比无显著意义。结论 :QT离散度可以作为临床判断室性心律失常严重性的一个指标。QT离散度的大小与心肌缺血的病理生理改变有密切关系。 Objective:To assess the relationship between QT dispersion and the grades of ventricular arrhythmias (VA). To make clear the factors affecting QTd and the clinical significance. Methods:QTd in 100 patients with all kinds of VA were measured on the surface simultaneous 12-lead electrocardiogram. All the patients were followed. Results:QTd of patients with VA above Lown grades Ⅲ was significantly higher than that below. Logistic multiple regression analysis between patients with increased QTd and without, including syncope, grades of VA ,causes of VA, and ST-T changes in the ECGs showed that the grades of VA and the ST-T changes in the ECGs were independently associated with QT dispersion. Of the 15 cases of syncope, 8 directly caused by cardiovascular disease had a higher mean value of QTd than that of other cases. There were no significant differences in QTd between two recordings in 40 patients with VA in comparison with those between normal controls. Conclusion:QT dispersion may well be a useful tool to evaluate the severity of ventricular arrhythmias. QT dispersion may be closely related to the changes of pathophysiology in myocardial ischemia. QT dispersion may help to judge the cause of syncope.
出处 《重庆医科大学学报》 CAS CSCD 2000年第2期159-161,共3页 Journal of Chongqing Medical University
关键词 QT离散度 室性心律失常 心电图描记术 QT dispersion Ventricular arrhythmias Electrocardiograph
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