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多西紫杉醇联合顺铂治疗原发灶不明癌的疗效观察 被引量:3

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摘要 目的察多西紫杉醇联合顺铂治疗原发灶不明癌的疗效。方法回顾性分析本院近3年来收治的25例原发灶不明癌患者,所有患者均具有可测量的病灶,各器官无功能衰竭现象。对25例患者使用多西紫杉醇和顺铂进行联合静脉化疗,每3周为1个疗程,2个疗程后对患者的疗效进行评价。在患者耐受的前提下,共完成5个疗程。结果 25例患者中共2例患者因不耐受而放弃治疗,其余23例患者的有效率为62%,对患者的中位进展时间和中位生存时间进行统计,分别为5个月和12个月。患者均伴有以下不良反应:呕吐、外周神经毒性、白细胞减少、肾毒性、肝毒性、心脏毒性。结论多西紫杉醇联合顺铂治疗原发灶不明癌的疗效显著,且临床使用安全可靠,对于患者而言其不良反应能够承受,所以值得在临床上得到推广和应用。
作者 迪吉
出处 《临床合理用药杂志》 2012年第18期57-57,共1页 Chinese Journal of Clinical Rational Drug Use
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