摘要
目的 :研究衰老形成的因素及探讨延缓衰老的方法。方法 :本实验从肾阳亏虚入手 ,选用传统古方双补丸 ,再加入淫羊藿、肉苁蓉两药组成加味双补丸一方。实验中 ,通过选用超氧化物歧化酶 (SOD)活性、丙二醛(MDA)含量、过氧化氢酶 (CAT)活性等七项指标 ,按试剂盒测定方法 ,从免疫、自由基、能量代谢角度对原方组、加味方组以及生理盐水组、维生素 E组延缓衰老的效果进行了比较研究。结果 :加味双补丸的作用效果明显优于其它各组 ,其中与生理盐水组相比 ,七项指标均有极其显著性差异 (P<0 .0 1 ) ;与维生素 E组相比 ,除丙二醛含量外 ,另六项指标有极其显著性差异 (P<0 .0 1 ) ;与原方组相比 ,除脾脏指数和丙二醛含量外 ,其余指标均差别显著 (P<0 .0 5)。结论 :肾阳亏虚为形成衰老的重要因素 。
Objective: To study the cause of aging and the way to delay it. Methods: An ancient prescription 'Shuangbuwan' was selected and then long spur epimedium and saline cistanche were put into it to form a new one. In this experiment, seven targets such as Superoxide dismutase(SOD),Malonaldehydic acid(MDA) and catalase(CAT) etc. were measured to compare the effects of four teams in their effect to delay aging. Results: The results showed that the effect of 'Jiaweishuangbuwan' is obviously supurior to those of other three teams at different levels. Conclusion: Therefore deficiency of kidney-yang is the main cause in aging.
出处
《锦州医学院学报》
2000年第1期13-16,共4页
Journal of Jinzhou Medical College
关键词
加味双补丸
中药实验
延缓衰老
Jiaweishuangbuwan
delay aging
experiment study
kidney-yang