摘要
目的 研究紫杉醇治疗对阿霉素、氟尿嘧啶在内的多种抗癌药耐药患者的临床疗效。 方法 32例病理证实的乳腺癌患者从前均接受过阿霉素、氟尿嘧啶治疗但无效 ,再给予紫杉醇治疗观察临床疗效。 结果 32例中 ,完全缓解 2例 ,占 6 3 % ,平均缓解期为 6个月。部分缓解 10例 ,占 31 3 % ,平均缓解期 4个月。有效率为37 5 %。 结论 紫杉醇对耐药乳腺癌的疗效较好 ,对于难治性晚期乳腺癌 。
Purpose:To investigate the clinical therapeutic effect of paclitaxol on drug resistant mammary carcinoma.Methods:32 cases of mammary carcinoma treated with adriamycin and fluorouracil with no effectiveness were given paclitaxol to observe its effect.Results:Complete response was seen in 2 with a response rate of 6.3% and partial response in 10 with a response rate of 31.3%.The average length of remission was 6 months in complete response and 4 months in partial response.The rate of effectiveness was 37.5%.Conclusions:Paclitaxol is effective in drug resistant mammary carcinoma. It is the first choice in the treatment of refractory advanced mammary carcinoma.
出处
《中国癌症杂志》
CAS
CSCD
2000年第2期153-154,共2页
China Oncology
关键词
紫杉醇
耐药性
乳腺癌
药物疗法
Paclitaxol
Drug resistance
Mammary carcinoma
Drug Therapy
