摘要
目的:观察损伤性大鼠肌筋膜疼痛模型触发点的肌电活动特征和组织形态学改变。方法:16只雄性SD大鼠(7周龄),随机分成对照组(A组)和实验组(B组)两组,实验组采取打击结合离心运动的实验方法对其进行连续8周造模干预。造模结束后,实验组与对照组均正常饲养4周。12周结束后对大鼠进行寻找触发点、记录触发点的肌电活动、病理解剖取材,然后进行触发点肌电分析和观察肌纤维病理组织形态。结果:A组大鼠没有出现触发点,B组大鼠平均出现2个触发点。正常对照组未发现自发肌电活动,实验组除了出现自发肌电活动外,其肌电电位是一种纤颤电位,与对照组的正常肌电电位有明显的区别。实验组的病理切片发现聚集的圆形或椭圆形肌纤维结节以及粗细相间的连续梭形肌纤维。结论:肌筋膜触发点是一种区域性堆集并具有肌电信号异常的挛缩肌纤维。此特征也反证了打击结合离心运动方法建立的大鼠触发点动物模型是有效的。
Objective： To observe the characteristics of electromyographical（EMG） activities and the changes of histomorphology in myofascialgia trigger points on rats＇ models from injuries. Method： A total of 16 male SD rats （7 weeks old） were randomly divided into control group （group A） and experimental group （group B）. Rats model of myofascialgia in group B were established by striking combining with eccentric exercise once per week, for continuous 8 weeks, then were reared normally and took rest for 4 weeks. At the end of the 2th week, all rats in two groups were examined to found the trigger points in palpable taut band, to record the pontaneous potential of EMG as well as local twitch response and to take the sections of musculi vastus medialis. The EMG of trigger points were analysed and the histomorphology of myofibers were ob- served. All the data were compared between two groups. Result： On an overage two palpable trigger points could be found in musculis vastus medialis of group B rats, but none in group A. There were local twitch responses and high frequency abnormal spontaneous electromyo- graphical activities, in all of the palpable trigger points and a pile of large round or elliptic myofibers in cross sections and alternate thick and thin continuous spindle myofibers in longitudinal sections. Conclusion： Myofascial trigger point was a pile of abnormal contractural myofibers with characteristics of abnor-real high frequency spontaneous electromyographica activities and histomorphology changes. Meanwhile, these characteristics demonstrated that rats＇ model of myofaseialgia trigger points from injuries established by striking combined with eccentric exercise was effective.
出处
《中国康复医学杂志》
CAS
CSCD
北大核心
2012年第7期594-599,共6页
Chinese Journal of Rehabilitation Medicine
基金
上海市重点学科资助项目(S30802)
广西自然科学基金资助项目(0832200)
关键词
肌筋膜疼痛触发点
损伤
自发电位
挛缩肌纤维
myofascialgia trigger point
injury
spontaneous potential
contractural myofiber
