摘要
众多学者把质子泵抑制剂(proton pump inhibitors,PPIs)治疗不应答的胃食管反流病(gastroesophageal reflux disease,GERD)称为难治性胃食管反流病,本病是当前消化系统疾病谱中最为顽固的治疗难题之一.近年来众多研究者运用多种诊察手段来研究本病,希望找到该病的发病机制.本文就最近国内外有关难治性GERD的诊断方案,发病机制及相关研究结果等内容作一综述.
Gastroesophageal reflux disease （GERD） that does not respond to treatment with proton pump inhibitors （PPIs） is widely accepted as refractory GERD, and it is one of the most stub- born digestive system diseases. In recent years, great efforts have been made to develop various diagnostic options for refractory GERD and to explore its pathogenesis. This article will review recent advances in diagnostic options and patho- genesis of refractory GERD.
出处
《世界华人消化杂志》
CAS
北大核心
2012年第19期1742-1746,共5页
World Chinese Journal of Digestology
基金
上海市卫生局科研课题基金资助项目
No.2010213~~
关键词
难治性胃食管反流病
质子泵抑制剂
诊断
发病机制
Gastroesophageal reflux disease
Proton pump inhibitors
Diagnostics
Pathogenesis
