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拟南芥和大白菜LUG蛋白家族的生物信息学分析

BIOINFORMATIC ANALYSIS OF LUG PROTEIN FAMILY IN ARABIDOPSIS THALIANA AND BRASSICA PEKINENSIS
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摘要 LUG蛋白属于WD40超家族基因,具有7个重复的WD40结构域,参与花器官的发育。本项研究系统鉴定了7个拟南芥和5个大白菜的LUG基因,并对这些基因编码的蛋白质序列进行了序列保守性和系统进化分析。结果表明,除了AtLUG6含有5个重复的WD40结构域之外,其余所有的LUG蛋白都具有7个重复的WD40结构域。在进化上,LUG蛋白家族可分为两个不同的亚家族,并且这种特征在拟南芥和大白菜分离之前就已经形成。 LUG protein family is a kind of WD40 super family genes which features the existence of 7 repeat WD40 domains. The members of this family play an important role in the development of flower. In this study, bioinformatics analysis identified 7 and 5 LUG genes in Arabidopsis and Chinese cabbage, respectively. The conserved sequences of these proteins were analyzed and a polygenetic tree was constructed based on the corresponding cystatin proteins from Arabidopsis and Chinese cabbage. The results suggested that, besides the AtLUG6 gene contains 5 repeat, all the other LUG genes all contain 7 repeat WD40 domains. The polygenetic analysis of these sequences indicated that they could be divided into two sub-family groups and the main character for LUG genes might have existed before the split of Chinese cabbage and Arabidopsis.
出处 《井冈山大学学报(自然科学版)》 2012年第4期42-47,60,共6页 Journal of Jinggangshan University (Natural Science)
基金 国家自然科学基金项目(31101553) 山东省博士基金项目(BS2010SW027)
关键词 拟南芥(Arabidopsis thaliana) 大白菜(Brassicapekinensis) 生物信息学分析 LUG蛋白 WD40结构 Arabidopsis Chinese cabbage LUG protein WD40 domain bioinformatic analysis
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参考文献12

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