摘要
目的探讨Bio-oss骨粉复合胶原膜在较大根尖囊肿术后骨腔修复中的临床效果。方法将63例根尖囊肿的患者随机分成实验组和对照组。第1组21例行根尖囊肿摘除后给予Bio-oss骨粉复合胶原膜填塞;第2组21例仅在术后骨腔外放置胶原膜;选择21例术后囊腔内不放置充填物作为对照组。进行第3、6、12个月的临床观察,分析2组X线下成骨变化。结果术后第3、6、12个月骨缺损区骨密度改变中骨粉复合胶原膜组均显著优于对照组(P<0.05),且以植骨复合胶原膜组骨密度增高明显,有较多的新骨小梁修复,实验组患牙未见瘘管形成,患牙保存较好。结论 Bio-oss复合胶原膜具有良好的生物相容性、骨传导和骨诱导作用,有利于骨组织长入及囊肿术后骨腔的修复,是一种理想的颌骨骨缺损的组织再生修复材料。
Objective To evaluate the clinical effects of the guided bone regeneration（Bio-oss） and collagen membrane in the treatment of larger radicular cyst.Methods 63 patients suffering radicular cyst were enrolled.All these cases were randomly divided into 3 groups.21 cases were treated with Bio-Gide and Bio-oss,and 21 were treated with collagen membrane in fossa only.The last 21 cases who received cyst extraction were the control group.Clinical parameters evaluated included changes in tooth mobility and the bone loss of the alveolar process according to radiograms preoperatively and at the 3rd,6th and 12th months after operation.Results At the 3rd,6th and 12th months postoperatively,two observation groups showed significantly more bone density increased according to the radiographs than the control group（P〈0.05）.The 1st group with Bio-oss and collagen membrane had the best efficacy.The teeth with radicular cyst remained well.Conclusions Bio-oss and absorbable collagen membranes show excellent bio-compatibility,which can accelerate the bone repair progress and can be successfully used for reconstruction of alveolar bone to obtain satisfactory clinical effects.
出处
《口腔医学》
CAS
2012年第6期359-361,364,共4页
Stomatology
