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78例三阴性乳腺癌的临床分析

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摘要 目的探讨三阴性乳腺癌的临床特征及预后情况。方法收集2000年3月至2007年8月间,本院收治的78例三阴性乳腺癌患者,回顾性分析其临床病理资料及预后相关因素。结果 78例TNBC患者的中位年龄为51岁(32～73岁),发病年龄≤35岁者9例(11.5%);绝经前患者47例(60.3%);有乳腺癌家族史(≥1个Ⅰ级亲属患乳腺癌)6例(7.7%),淋巴结阳性患者49例(62.8%),肿瘤最大径≥5cm者12例(15.4%),浸润性导管癌66例(85%);病理分级Ⅰ级12例(15.4%),Ⅱ级48例(61.5%),Ⅲ级18例(23.15%);病理分期Ⅰ期11例(14.1%),Ⅱ期40例(51.3%),Ⅲ期22例(28.2%),Ⅳ期5例(6.4%)。术后3年内复发转移者37例(78.7%),3年总生存率69.4%,3年无疾病进展生存率为48.6%。结论三阴性乳腺癌具有确诊时原发肿瘤较大、病理分期较晚、病理分级较高、淋巴结转移数目较多、术后早期复发转移率较高等特征,淋巴结转移数目是三阴性乳腺癌预后的独立指标。
作者 任伟丽
机构地区 浙江省上虞市人民医院
出处 《浙江创伤外科》 2012年第3期341-343,共3页 Zhejiang Journal of Traumatic Surgery
关键词 三阴性乳腺癌 临床特征 预后相关因素
分类号 R737.9 [医药卫生—肿瘤]
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参考文献11

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