摘要
目的应用炎症性肠病生存质量问卷(IBDQ)评价炎症性肠病(IBD)患者的生存质量。方法选择172例门诊及住院IBD患者进入本研究,IBD病情评估:溃疡性结肠炎(UC)参考True-Love标准分为轻型、中型、重型。克罗恩病(CD)依据Harvey和Bradshaw标准分组:积分<4分为缓解期,4～8分为中度活动期,≥9分为重度活动期。调查以面谈方式进行。营养风险评估采用NRS2002方法。结果 172例患者中UC 102例,CD 70例;男95例,女77例。患者IBDQ总分及其4个维度评分与病情严重程度呈负相关(P<0.001)。CD组缓解期和活动期的IB-DQ总分间差异有统计学意义(P<0.001),但中度活动组和重度活动组的IBDQ总分间差异无统计学意义(P=0.366)。患者疾病诊断(UC或CD)、年龄、性别、医疗费用以及营养风险等因素与IBDQ评分无显著相关。结论IBDQ与IBD患者病情严重程度呈负相关,可有效评价患者的生存质量。
Objective To assess the health-related quality of life in patients with inflammatory bowel disease（IBD） by inflammatory bowel disease questionaire（IBDQ）.Methods Totally 172 patients from the in-hospital and clinical services in Peking Union Medical College Hospital were enrolled in this study.The severity of IBD was evaluated by Truelove criteria for ulcerative colitis（UC） and Harvey-Bradshaw criteria for Crohn′s disease（CD）.Patients were divided into three groups：mild group（or remission group）,moderate group,and severe group.IBDQ was completed by interview.Nutritional status was evaluated by nutritional risk screening（NRS2002）.Results Totally 172 patients（UC,n=102;CD,n=70;male,n=95,female,n=77） completed the IBDQ.The total score of IBDQ as well as all 4 domains negatively correlated with disease activity（P0.001）.The IBDQ was able to discriminate between active and inactive CD（P0.001）,but it could not discriminate between moderate active and severe active CD（P=0.366）.There were no significant correlations between the total score of IBDQ and patient′s diagnosis（UC or CD）,age,sex,medical insurance,or nutritional risk（P0.05）.Conclusion IBDQ is negatively correlated with the severity of IBD and therefore can be used to assess the health-related quality of life of patients with IBD.
出处
《中国全科医学》
CAS
CSCD
北大核心
2012年第17期1974-1976,共3页
Chinese General Practice
关键词
炎症性肠病
炎症性肠病生存质量问卷
健康相关生存质量
Inflammatory bowel disease
Inflammatory bowel disease questionnaire
Health related quality of life
