摘要
目的:观察酮咯酸氨丁三醇预防瑞芬太尼全麻苏醒期疼痛及躁动的临床效果。方法:选择40～60岁择期行腹腔镜胆囊手术患者100例,ASA I～II级,随机分为两组,每组50例,观察组手术结束前30min静脉滴注酮咯酸氨丁三醇30mg,对照组手术结束前30min静脉滴0.9%氯化钠1mL,观察两组患者自主呼吸恢复时间、苏醒时问、拔管时间以及拔管后15、30min疼痛评分和烦躁程度评级。结果:两组自主呼吸恢复时间、苏醒时间、拔管时间差异均无统计学意义(P>0.05);观察组拔管后15、30min疼痛评分及躁动程度评级明显低于对照组,差异有统计学意义(P均<0.01)。结论:酮咯酸氨丁三醇可以预防瑞芬太尼全麻苏醒期疼痛和躁动。
Objective. To observe the clinical effects of ketorolac tromethamine for prevention of pain and agitation during anesthesia recovery period after remifentanil anesthesia. Method. A total of 100 cases scheduled for laparoscopic cholecystectomy aged between 40-60 years, categoried as ASA Ⅰ-Ⅱ stage, were randomly divided into two groups with 50 cases in each. 30 mg of ketorolac tromethamine was infused intravenously for experimental group 30 min before the end of the operation; 1 mL of 0.9% sodium chloride was given for the control group at the same time point. Spontaneous breathing recovery time, recovery time and extubation time were recorded. Pain score and agitation severity score were evaluated 15 and 30 min after extubation. Results. No significant differences were found in spontaneous respiratory recovery time, recovery time, extubation time between the two groups （ P〉0.05 ）; the pain score and agi- tation severity score of the experimental group were both significantly higher than that in the control group （ P〈 0.01 ）. Conclusions： Ketorolac tromethamine can prevent pain and agitation during anesthesia recovery period after remifentanil anesthesia.
出处
《海南医学院学报》
CAS
2012年第7期962-963,966,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210242)~~
