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非酮症高血糖合并偏侧舞蹈症3例并文献复习 被引量:2

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摘要 目的:探讨非酮症高血糖合并偏侧舞蹈症(NC-NH)的临床表现、发病机制、影像学表现及治疗。方法:我院2009年4月至2011年5月收治非酮症高血糖合并偏侧舞蹈症患者3例,对其临床资料进行分析讨论并复习近20年文献,总结其临床特点、发病机制、影像学表现及治疗。结果:3例患者均为老年人,急性起病。舞蹈样症状可累及单侧或双侧肢体或面部。既往有或无糖尿病史。发病时血糖水平为15~31.8mmol/L,尿酮阴性。头部影像学检查:CT显示患肢对侧尾状核头和壳核呈高密度,MRI于T1加权像呈高信号,T2加权像呈稍低或等信号,DWI像呈稍高或等信号。首选降糖、补液治疗,必要时联合应用氟哌啶醇药物治疗效果较好。结论:非酮症高血糖、偏侧舞蹈症以及CT表现为基底节区高密度和(或)MRI表现为基底节区T1高信号,可能构成典型的HC-NH表现三联征;影像学改变可能与高血糖导致血液高黏度、低灌注、血脑屏障破坏有关。采用降糖、氟哌啶醇治疗效果较好。
出处 《泸州医学院学报》 2012年第3期315-317,共3页 Journal of Luzhou Medical College
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参考文献10

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