摘要
目的：了解小儿手术前后血液流变特性的变化规律，探讨手术创伤对小儿全身性的影响，指导小儿因手术期处理。方法：使用自身前后对照，并取小儿健康对照及同期成年患者对照，全部病例无影响血液流变特性疾病，未服用影响血液流变特性药物，体温正常，分别于术晨，术后即刻，术后1天抽血抗凝送检测定全血粘度（WBV），血浆粘度（PV），纤维蛋白原（Tidg），血沉（ESR），红细胞压积（HCT），红细胞刚性指数（IR）及聚集性指数（NR）。结果：①对照组和各研究组术前以及小儿非输血组手术前后比较，其血液流变物性各项指标均无明显差异（P＜0．05）。②小儿输血组手术前后比较：术后即刻无明显改变，术后1天其NR与IR均有明显升高，尤以后者明显（P＜0．01）。③成年手术组前后其WBV、PV、IRNR与Tidg等均有显著差异性（P＜0．01）。结论：一般手术对小儿血液流变特性的影响不如成人明显，长时间的手术或重大创伤可影响红细胞的变形能力和聚集性并进而影响微循环灌注和组织供氧。
Objective: To observe the Peri-opertive hemorrheological Parameters in Pediatric patients and the effects on the whole they produced by surgical trauma and to guide the Peri-operative management.Methods: This was a pre-after controlled study. harameters, such as HCT, ESR, PV, WBV, IR, NR,Tidg were determined pre-and post-operatively. Results: All parameters determined pre-operatively were stable. Parameters determined after surgery in the patients without transfusion were also stable, but the WBV, NR, PV had relatively increased after surgery in the group of adults and IR, NR increased in the group of children with transfusion. Conclusions: The change of parameters of flow-properties of blood in children is less obvious than that of the adults. The authors emphasize that it is important to deal with the children at the high coagulation status after operation.
出处
《广州医药》
2000年第1期7-9,共3页
Guangzhou Medical Journal
