摘要
本文报告11例环状肉芽肿,1例为限局型;10例为播散型。皮损是丘疹或环状浸润斑块病理上有栅栏状肉芽肿及单核一组织细胞浸润两型。本病可能是原发性免疫复合物血管炎,淋巴细胞介导的迟发型过敏反应导致胶原纤维的变性,或伴有糖尿病。本病须与类脂质渐进性坏死,体癣、扁平苔癣的皮损鉴别。用类固醇激素治疗效果好,但可能复发。
Eleven cases of granuloma annulare (GA) are reported. Ten cases were generalized; one case was localized The lesions were papules and annular plaques. The histopathological feature of the disease was of a palisading granuloma or mononuclear histiocyte infiltrate type. Granuloma annulare is a disease of unknown etiology It is possibly a primary immune complex vasculitis or a lymphocyte mediated, delayed hypersensitivity reaction leading to alteration of collagen Some patients have accompanying diabetes. The differential diagnosis of the disease includes necrobiosis lipoidica, lichen planus, or tinea corporis Steroids are effective in treating granuloma annulare but relapses may occur
出处
《北京医学》
CAS
北大核心
1989年第1期23-25,共3页
Beijing Medical Journal
