摘要
目的:探讨米索前列醇预防剖宫产产后出血的临床效果。方法:以我院117例剖宫产者为研究对象,分组通过不同给药途径给予米索前列醇和宫缩素,观察产后出血量及不良反应情况。结果:口服或直肠置入米索前列醇产妇产后平均出血量均明显少于使用缩宫素者;而直肠置入效果明显优于口服而不良反应少,比较差异均有统计学意义(P<0.05)。结论:剖宫产术中使用米索前列醇直肠给药,预防产后出血效果好,不良反应小,对减少产后出血量,降低产妇的病死率有重要意义,值得临床进一步研究推广。
Objective：To investigate the clinical effect of Misoprostol in preventing postpartum hemorrhage. Methods： 117 cases of maternal underwent cesarean sections were grouped and given Misoprostol and Oxytocin through different routes, the results of postpartum hemorrhage and adverse reactions were observed. Results： The average amount of postpartum hemorrhage both in oral and rectal placement group of using misoprostol were significantly less than the group of using oxytocin; however, the efficacy of rectal placed was better than the oral with less of adverse reactions, the differences were statistically significant （P〈0.05）. Conclusion： The effect of using misoprostol rectally in preventing postpartum hemorrhage was good for cesarean section with less adverse reactions, which was important in reducing postpartum hemorrhage and maternal mortality, and worthy of further research and promotion.
出处
《北方药学》
2012年第6期9-10,共2页
Journal of North Pharmacy
关键词
米索前列醇
剖宫产
产后出血
预防
疗效
Misoprostol Cesarean section Postpartum hemorrhage Prevention Efficacy
