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逆行开通技术治疗下肢动脉闭塞性病变 被引量:8

Treatment of lower extremity arterial occlusive disease through retrograde access
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摘要 目的探讨在介入治疗下肢动脉闭塞性病变导丝无法顺行通过闭塞段时改用逆行开通技术的临床意义。方法回顾性分析27例下肢动脉闭塞性病变患者,男17例、女10例,年龄32-89岁,平均(70±12)岁。27例中下肢动脉硬化性闭塞症18例、糖尿病足7例、血栓闭塞性脉管炎2例。按Fontaine分期,Ⅱ期6例、Ⅲ期11例、Ⅳ期10例。在导丝无法顺行开通真腔、进入内膜下无法重返真腔或穿出血管外后,采用经足背动脉、胫后动脉穿刺或切开显露及利用足踝部胫后动脉、腓动脉、足背动脉的侧支血管进行逆行开通闭塞血管,再进行球囊扩张术和支架植入术。结果27例手术均获得成功,血管开通后患者下肢缺血症状即刻得到改善。仅3例出现穿刺处血肿、1例足背动脉切开后足趾麻木,无严重围手术期并发症。术后5d平均踝肱指数由术前的0.37±0.11增加到0.85±0.12。结论逆行开通技术可以作为常规正向开通技术治疗下肢动脉闭塞性病变失败时的一种补救方法,可以明显提高介入手术的成功率。 Objective To explore the clinical significance of retrograde access for the interventional treatment of lower extremity arterial occlusive diseases when the occluded segment of lower extremity artery could not be reached through antegrade access. Methods Twenty-seven cases (male 17, female 10; age range 32-89 years) were retrospectively investigated, including 18 with lower limb arteriosclerosis obliterans, 7 with diabetic foot and 2 with thromboangiitis obliterans. According to the Fontaine staging, 6 cases were classified as FontaineⅡ, 11 were classified as Fontaine Ⅲ and 10 were classified as Fontaine Ⅳ. All cases underwent endovascular operation through antegrade access first with an attempt to cross the occlusive segment, but in vain. So retrograde access was tried via puncture of pedis dorsalis or posterior tibial artery or exposure of lateral branches of posterior tibial artery, peroneal artery or dorsal artery by open surgery, which followed by Percutaneous transluminal angiography and (or) stenting. Results The operation through retrograde access was successful in all cases with obvious improvement of ischemic symptoms. Hematoma at the puncture site occurred in 3 patients, and paresthesia of toes occurred in 1 after dorsalis pedis arteriotomy. No severe perioperative complication occurred. The average ankle brachial index increased from 0. 37 ± 0. 11 preoperatively to 0. 85 ±0. 12 postoperatively. Conclusions Retrograde access could be used as an alternative strategy in lower extremity arterial occlusive diseases when the occluded segment could not reach through antegrade access.
出处 《中华放射学杂志》 CAS CSCD 北大核心 2012年第6期557-560,共4页 Chinese Journal of Radiology
关键词 放射学 介人性 动脉闭塞性疾病 逆向开通技术 Radiology, interventional Arterial occlusive diseases Skill of retrograderecanalization
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  • 1殷敏毅,黄新天,陆信武,李维敏,黄英,陆民,蒋米尔.TASCⅡ C、D型股腘动脉闭塞腔内治疗的操作技巧与疗效分析[J].中国血管外科杂志(电子版),2011,3(2):94-97. 被引量:10
  • 2刘昌伟,吴巍巍.重症下肢缺血的外科治疗:问题与对策[J].中国血管外科杂志(电子版),2010,2(2):67-70. 被引量:4
  • 3谷涌泉,张建,郭连瑞,汪忠镐,张淑文,齐立行,徐娟,冀冰心,李建新,俞恒锡,李学锋,崔世军,罗涛,武欣,董宗俊.自体骨髓干细胞移植治疗下肢严重缺血:32例报告[J].中国临床康复,2004,8(35):7970-7972. 被引量:69
  • 4李伟,张小明,张学民,沈晨阳,李清乐.弹簧支架在下肢动脉硬化性狭窄和闭塞治疗中的应用[J].中华普通外科杂志,2006,21(12):856-858. 被引量:6
  • 5赵阳,丁丽娜,苗俊英.内皮祖细胞的研究进展[J].中国现代普通外科进展,2006,9(5):257-258. 被引量:3
  • 6Traiffrt E, Angot E, Ruat M. Sonic Hedgehog signaling in the mammalian brain[J]. J Neurochem, 2010,113(3) :576 -590.
  • 7Ingham P W, McMahon A P. Hedgehog signaling in animal development:paradigms and principies[J]. Genes Dev, 2001,15 (23) :3059- 3087.
  • 8Kusano K F, Allendoerfer K L, Munger W, et al. Sonic hedgehog induces arteriogenesis in diabetic vasa nervo ixlm and restores function in diabetic neuropathy[J]. Arterioscler Thromb Vasc Biol , 2004,4(1) :105-128.
  • 9Wang Y, Bai Y, Qin L, et al. Interferon-gamma induces human vascular smooth muscle cell proliferation and intirnal expansion byphosphtidylinositol 3 kinase dependent mammali an target of rapamycin raptor complex 1 activation[J]. Circ Res, 2007,101(6) :560-569.
  • 10Nagase T, Nagase M, Yoshimura K, et al. Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling : possible roles of motor neurons [ J ]. Genes to Cells, 2005,10(6) :595-604.

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