摘要
5-羟色胺作为参与针刺效应的重要中枢调控物质,在阐述针刺效应作用机制中有着重要的研究价值。大量实验研究已证明针刺能显著影响中枢5-羟色胺的含量及活动,且不同条件下针刺对5-羟色胺影响不同。本文就近年来国内外中枢5-羟色胺及其受体在针刺效应中的作用研究现状作了回顾,并结合以往的研究提出新的看法和研究思路。
As for an important central regulatory neurotransmitter involving acupuncture effect, serotonin（5-HT）is worthy of being paid with more attention. In the present paper, the authors review development of researches on the involvement of 5-HT and its receptor subunits in pain perception, acupuncture analgesia, and other effects of acupuncture （anti-depression, weight-re- duction, etc. ）. Many studies showed that acupuncture intervention could modulate the content and activity of central 5-HT, and these changes varied under different conditions. Hence, the relationship between 5-HT and other neurotransmitters in acupuncture analgesia and its different functions in different regions of the central nervous system should be considered comprehensively.
出处
《针刺研究》
CAS
CSCD
北大核心
2012年第3期247-251,共5页
Acupuncture Research
基金
国家自然科学基金(30801484)
安徽省自然科学基金(090413112)
安徽高校省级自然科学研究项目(KJ 2011A188)
安徽中医学院科学研究基金(2010zr 016B)资助
关键词
5-羟色胺
中枢神经系统
针刺镇痛
电针
Serotonin
Central nervous system
Acupuncture analgesia
Electroacupuncture
