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89锶在控制乳腺癌骨转移疼痛及改善生存质量中的效果研究

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摘要 目的:探讨89锶用于控制乳腺癌骨转移疼痛的临床效果。方法:选取乳腺癌骨转移且伴有中度以上疼痛患者130例,随机分为有可比性的三组,其中A组35例,给予帕米磷酸二钠治疗;B组35例,给予89锶治疗;C组60例,给予二者联合治疗。对三组患者疼痛缓解情况及病灶改善情况进行比较分析。结果:单独使用89锶治疗乳腺癌骨转移疼痛及缩小病灶是有效的,与单独使用帕米磷酸二钠效果相似,比价差异不明显,无统计学意义(P>0.05),但是89锶与帕米磷酸二钠联合应用,可以有效提高治疗效果,与二者单独使用相比,差异有统计学意义(P<0.05)。结论:单独使用89锶可以达到较好的镇痛和改善病灶作用,从而改善患者生存质量;但是与帕米磷酸二钠联合应用,治疗效果更佳,建议临床联合应用。
出处 《亚太传统医药》 2012年第6期189-190,共2页 Asia-Pacific Traditional Medicine
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