摘要
甲巯丙脯酸(captopril)对多种致炎剂所致的肿胀和琼脂肉芽组织增生均有明显抑制作用。其作用可能是通过增加PGs(前列腺素)类物质的合成而发挥上述作用的。
Anti-inflammatory effect of captopril were shown
by depressing the increased capillary permeability (in-
duced by dimethyl-benzene) and the inflammatory
edema of ear induced by dimethyl-benzene in mice.
The proliferation of granuloma (induced by subcutan-
eous implantation of agar) in rats was inhibited by cap-
topril. The mechanism of above mentioned effects
may be the increasing of PGS synthesis.
出处
《中国药学杂志》
CAS
CSCD
北大核心
1990年第9期531-532,共2页
Chinese Pharmaceutical Journal