多环芳烃-DNA加合物检测及其在流行病学研究中的应用
摘要
多环芳烃是环境中广泛存在的有机污染物,其与DNA形成的加合物是DNA损伤的重要生物标志.在流行病学研究中,检测多环芳烃-DNA加合物水平可以评价DNA损伤状态,进而与相关疾病、环境暴露、基因型等发生联系.本文就多环芳烃-DNA加合物的检测方法、原理、优缺点及在流行病学研究中的应用做一综述.
出处
《中国生育健康杂志》
2012年第3期236-239,共4页
Chinese Journal of Reproductive Health
基金
国家自然科学基金（31071315）
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