摘要
目的 研究西安地区献血员中庚型肝炎病毒 (HGV)与乙型肝炎病毒 (HBV)、丙型肝炎病毒 (HCV)混合感染情况 .方法 采用 EL ISA方法检测献血员 34 2例血清中的 HBs Ag和抗 - HCV,用逆转录聚合酶反应 (RT- PCR)检测 HGV- RNA.结果 发现在西安地区 HBs Ag与抗 - HCV均为阴性的献血员中 HGV- RNA阳性率为 3.5 0 % (7/ 2 0 0 ) ,HBs Ag阳性 ,抗 -HCV阴性献血员中 HGV- RNA阳性率为 8.77% (5 / 5 7) ,HB-s Ag阴性而抗 - HCV 阳性献血员中 HGV- RNA阳性率为9.2 6 % (1 0 / 1 0 8) ,HBs Ag与抗 - HCV均为阳性的献血员 HGV-RNA阳性率为 1 5 .6 3% (5 / 32 ) .结论 HGV与 HBV和 (或 )HCV联合感染的阳性率要明显高于
AIM To investigate the coinfection of HGV with hepatitis B virus (HBV) and hepatitis C virus (HCV) of blood donors in Xi’an area. METHODS HBsAg, anti HCV and HGV RNA were detected by ELISA and RT PCR, respectively. RESULTS The experimental data showed that the positive rates for HGV RNA of serum samples were 3 50% (7/200) among those were negative for both HBsAg and anti HCV, 8.77% ( 5/57) among those were positive forHBsAg but negative for anti HCV, 9.26% ( 10/108) among those were negative for HBsAg but positive for anti HCV and 15.63% (5/32) in the group in which all samples were positive for both HBsAg and anti HCV. CONCLUSION The results confirmed that HGV has a transmission route similar to that for HBV and HCV and that the coinfection of HGV with HBV and (or) HCV is more frequent than HGV infection alone.
出处
《第四军医大学学报》
2000年第2期146-147,共2页
Journal of the Fourth Military Medical University
