摘要
目的:观察复肝注射液对H22肝癌模型小鼠的疗效,并探讨相关作用机制。方法:制备H22肝癌模型,分成对照组、低剂量组、中剂量组、高剂量组、迈青组五组,观察对模型小鼠抑瘤率、生存时间、体重的影响及对低剂量环磷酰胺的增效作用。结果:复肝注射液对小鼠肝癌具有明显抑制作用,能延长小鼠的生存时间,并表现出对化疗药物的协同增效作用。结论:复肝注射液治疗肝癌疗效明显。
Objective：To observe the effect of Fugan injection on H22 hepatocarcinoma model mice and explore the related mechanism.Methods：H22 hepatocarcinoma models were prepared.The models were divided into five groups： control group,low-dose group,medium-dose group,high-dose group and Maiqing group.The tumor-suppressor rate,survival time and weight of models were detected.The synergistic effect of low-dose cyclophosphamide was also be observed.Results：Fugan injection could inhibit hepatocarcinoma,prolong the survival time and had synergistic effect by combined with chemotherapy drugs.Conclusion：Fugan injection has obvious therapeutic effect on hepatocelluar carcinoma.
出处
《山东中医药大学学报》
2012年第3期248-250,共3页
Journal of Shandong University of Traditional Chinese Medicine
关键词
复肝注射液
肝癌
实验研究
Fugan injection
hepatocarcinoma
experimental study
